12月19日新加坡国立大学刘小钢教授学术讲座预告

    报告题目：Upconversion Nanocrystals: The Search for High Efficiency Luminescent Bioprobes
    报告时间：12月19日下午14:00
    报告地点：存中十楼报告厅
    报告人：刘小钢教授  新加坡国立大学
    
    报告人简介：
    刘小钢博士，2004年获得西北大学博士学位，美国麻省理工学院博士后。于2006年加入新加坡国立大学化学系，现为新加坡国立大学化学系终身教授，同时在新加坡科学院的材料工程所任高级研究员。刘小钢博士的研究领域包括纳米材料制备和组装，生物无机化学和超分子化学等，尤其在稀土离子掺杂上转换发光纳米材料性能的研发及其在3D显示，生物成像，分子检测和光学防伪等应用领域取得了突破性进展。刘小钢博士在国际顶尖期刊发表研究论文100余篇，其中包括Science，Nature，Nature Materials，Nature Nanotechnology和Nature Chemistry等nature子刊20余篇，以及Chemical Society Reviews，Angewandte Chemie International Edition，Journal of the American Chemical Society和Advanced Material等，被引用~17000次，h-指数为58。此外，刘小钢博士曾荣获英国皇家化学会《化学会评论》新科学家奖（2012）、台湾国家科学委员会讲学奖（2012）、新加坡国立大学青年研究学者奖（2011）以及巴斯夫-新加坡国家化学研究院材料化学奖（2010）等。最为重要的是，刘小钢博士于2016年获得了新加坡总统科学奖，该奖项代表了新加坡科研界最高的荣誉。
    
    报告摘要：
    Lanthanide-doped nanoparticles exhibit unique luminescent properties, including a large Stokes shift, a sharp bandwidth of emission, high resistance to optical blinking, and photobleaching. Uniquely, they can also convert long-wavelength stimulation into short-wavelength emission. These attributes offer the opportunity to develop alternative luminescent labels to organic fluorophores and quantum dots. In recent years, researchers have taken advantage of spectral-conversion nanocrystals in many important biological applications, such as highly sensitive molecular detection and autofluorescence-free cell imaging. With significant progress made over the past several years, we can now design and fabricate nanoparticles that display tailorable optical properties. In particular, we can generate a wealth of color output under single-wavelength excitation by rational control of different combinations of dopants and dopant concentration. By incorporating a set of lanthanide ions at defined concentrations into different layers of a core-shell structure, we have expanded the emission spectra of the particles to cover almost the entire visible region, a feat barely accessible by conventional bulk phosphors. In this talk, I will highlight recent advances in the broad utility of upconversion nanocrystals for multimodal imaging, bio-detection, display and photonics.